Vascular Effects of the Precision Interventions for Severe Asthma (VASC-PreCISE)

At a Glance

The prevalence of asthma, a chronic inflammatory condition, is higher in Wisconsin than the national average, and can lead to an increased risk of cardiovascular disease. Asthma also disproportionately afflicts children and ethnic minorities. Matthew Tattersall, DO, MS, Department of Medicine will lead the project Vascular Effects of Precision Interventions for Severe Asthma (VASC-PreCISE), which aims to find the ideal precision asthma therapy to address inflammation in asthmatics, and ultimately to reduce their risk for cardiovascular disease. Project collaborators include James Stein, MD, and Loren Denlinger, MD, PhD, of the Department of Medicine. Finding the correct, precision, novel therapy to address each asthmatics’ unique inflammation pattern has the potential to reduce patients’ cardiovascular risk. Moreover, addressing chronic inflammation at an early age may completely alter the cardiovascular risk of generations of asthmatic individuals.