Preconception Weight Loss Strategy Impact on Gestational Glycemia, Milk Lipids and Offspring Islet Health

Awarded in 2024
Updated Sep 22, 2025

At a Glance

Obesity before pregnancy increases the risk of complications such as gestational diabetes, preeclampsia and adverse outcomes for both parent and child. In Wisconsin, nearly 30% of people giving birth have obesity, underscoring the urgent need for effective preconception interventions. This project will compare four weight loss strategies to assess their effects on gestational glycemia, milk lipid composition and offspring pancreatic health. Findings will provide critical evidence to guide safe, effective weight loss recommendations before pregnancy, helping reduce intergenerational risk of diabetes and improve maternal-child health outcomes.