Role of the EnvCT in SIVmac Viral Fitness

Awarded in 2024
Updated Sep 8, 2025

At a Glance

The Role of the EnvCT in SIVmac Viral Fitness project is exploring a hidden part of the HIV virus that could open new doors for vaccine development. While most efforts focus on the virus’s outer surface, this research studies the envelope’s cytoplasmic tail (EnvCT) to see how it influences immune recognition and viral survival. By testing antibody responses and mapping how EnvCT interacts with host cells, the project aims to uncover new strategies to make HIV more vulnerable to prevention and treatment.